Annexin A2 Enhances Complement Activation by Inhibiting Factor H()

Factor H is a circulating protein that regulates activation of the alternative pathway (AP) of complement. Mutations and genetic variations of factor H are associated with several AP-mediated diseases, highlighting the critical role of factor H in AP regulation. AP-mediated inflammation is typically...

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Publicat a:J Immunol
Autors principals: Renner, Brandon, Tong, Hua Hua, Laskowski, Jennifer, Jonscher, Karen, Goetz, Lindsey, Woolaver, Rachel, Hannan, Jonathan, Li, Yong Xing, Hourcade, Dennis, Pickering, Matthew C., Holers, V. Michael, Thurman, Joshua M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724541/
https://ncbi.nlm.nih.gov/pubmed/26729803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500793
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