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KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) is very aggressive and lacks specific therapeutic targets. Ribosome RNAs (rRNAs) are central components of ribosomes and transcribed in nucleoli, and the level of rRNA transcription greatly affects ribosome production and cell proliferation. We have reported that...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Okamoto, Kengo, Tanaka, Yuji, Ogasawara, Sachiko, Obuse, Chikashi, Nakayama, Jun-ichi, Yano, Hirohisa, Tsuneoka, Makoto
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677663/
https://ncbi.nlm.nih.gov/pubmed/31413816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27092
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