Metformin activates KDM2A to reduce rRNA transcription and cell proliferation by dual regulation of AMPK activity and intracellular succinate level

by Tanaka, Yuji, Konishi, Akimitsu, Obinata, Hideru, Tsuneoka, Makoto
Published in Sci Rep (2019)

Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription

by Tanaka, Yuji, Obinata, Hideru, Konishi, Akimitsu, Yamagiwa, Noriyuki, Tsuneoka, Makoto
Published in Cells (2020)

Mild Glucose Starvation Induces KDM2A-Mediated H3K36me2 Demethylation through AMPK To Reduce rRNA Transcription and Cell Proliferation

by Tanaka, Yuji, Yano, Hirohisa, Ogasawara, Sachiko, Yoshioka, Sho-ichi, Imamura, Hiromi, Okamoto, Kengo, Tsuneoka, Makoto
Published in Mol Cell Biol (2015)

KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells

by Okamoto, Kengo, Tanaka, Yuji, Ogasawara, Sachiko, Obuse, Chikashi, Nakayama, Jun-ichi, Yano, Hirohisa, Tsuneoka, Makoto
Published in Oncotarget (2019)

Increased Expression of a Myc Target Gene Mina53 in Human Colon Cancer

by Teye, Kwesi, Tsuneoka, Makoto, Arima, Nobuyuki, Koda, Yoshiro, Nakamura, Yasuhiro, Ueta, Yoichi, Shirouzu, Kazuo, Kimura, Hiroshi
Published 2004

JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation

by Tanaka, Yuji, Okamoto, Kengo, Teye, Kwesi, Umata, Toshiyuki, Yamagiwa, Noriyuki, Suto, Yutaka, Zhang, Yi, Tsuneoka, Makoto
Published 2010