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JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation
The rate-limiting step in ribosome biogenesis is the transcription of ribosomal RNA, which is controlled by environmental conditions. The JmjC enzyme KDM2A/JHDM1A/FbxL11 demethylates mono- and dimethylated Lys 36 of histone H3, but its function is unclear. Here, we show that KDM2A represses the tran...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876952/ https://ncbi.nlm.nih.gov/pubmed/20379134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.56 |
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