JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation

The rate-limiting step in ribosome biogenesis is the transcription of ribosomal RNA, which is controlled by environmental conditions. The JmjC enzyme KDM2A/JHDM1A/FbxL11 demethylates mono- and dimethylated Lys 36 of histone H3, but its function is unclear. Here, we show that KDM2A represses the tran...

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Hlavní autoři: Tanaka, Yuji, Okamoto, Kengo, Teye, Kwesi, Umata, Toshiyuki, Yamagiwa, Noriyuki, Suto, Yutaka, Zhang, Yi, Tsuneoka, Makoto
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876952/
https://ncbi.nlm.nih.gov/pubmed/20379134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.56
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