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KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) is very aggressive and lacks specific therapeutic targets. Ribosome RNAs (rRNAs) are central components of ribosomes and transcribed in nucleoli, and the level of rRNA transcription greatly affects ribosome production and cell proliferation. We have reported that...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Okamoto, Kengo, Tanaka, Yuji, Ogasawara, Sachiko, Obuse, Chikashi, Nakayama, Jun-ichi, Yano, Hirohisa, Tsuneoka, Makoto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677663/
https://ncbi.nlm.nih.gov/pubmed/31413816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27092
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