KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) is very aggressive and lacks specific therapeutic targets. Ribosome RNAs (rRNAs) are central components of ribosomes and transcribed in nucleoli, and the level of rRNA transcription greatly affects ribosome production and cell proliferation. We have reported that...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Okamoto, Kengo, Tanaka, Yuji, Ogasawara, Sachiko, Obuse, Chikashi, Nakayama, Jun-ichi, Yano, Hirohisa, Tsuneoka, Makoto
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677663/
https://ncbi.nlm.nih.gov/pubmed/31413816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27092
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