AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs)

BACKGROUND: The chemical carcinogen 3-methylcholanthrene (3MC) binds to the aryl hydrocarbon receptor (AHR) that regulates the expression of cytochrome P450 (CYP) enzymes as CYP1B1, which is involved in the oncogenic activation of environmental pollutants as well as in the estrogen biosynthesis and...

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Библиографические подробности
Опубликовано в: :J Exp Clin Cancer Res
Главные авторы: Cirillo, Francesca, Lappano, Rosamaria, Bruno, Leonardo, Rizzuti, Bruno, Grande, Fedora, Guzzi, Rita, Briguori, Sara, Miglietta, Anna Maria, Nakajima, Miki, Di Martino, Maria Teresa, Maggiolini, Marcello
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676524/
https://ncbi.nlm.nih.gov/pubmed/31370872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1337-2
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