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AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs)

BACKGROUND: The chemical carcinogen 3-methylcholanthrene (3MC) binds to the aryl hydrocarbon receptor (AHR) that regulates the expression of cytochrome P450 (CYP) enzymes as CYP1B1, which is involved in the oncogenic activation of environmental pollutants as well as in the estrogen biosynthesis and...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Cirillo, Francesca, Lappano, Rosamaria, Bruno, Leonardo, Rizzuti, Bruno, Grande, Fedora, Guzzi, Rita, Briguori, Sara, Miglietta, Anna Maria, Nakajima, Miki, Di Martino, Maria Teresa, Maggiolini, Marcello
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676524/
https://ncbi.nlm.nih.gov/pubmed/31370872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1337-2
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