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Computational Approaches for the Discovery of GPER Targeting Compounds

Estrogens exert a panel of biological activities mainly through the estrogen receptors α and β, which belong to the nuclear receptor superfamily. Diverse studies have shown that the G protein-coupled estrogen receptor 1 (GPER, previously known as GPR30) also mediates the multifaceted effects of estr...

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Publicado en:Front Endocrinol (Lausanne)
Autores principales: Grande, Fedora, Occhiuzzi, Maria A., Lappano, Rosamaria, Cirillo, Francesca, Guzzi, Rita, Garofalo, Antonio, Jacquot, Yves, Maggiolini, Marcello, Rizzuti, Bruno
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417359/
https://ncbi.nlm.nih.gov/pubmed/32849301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00517
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