The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells

The inhibition of the G protein-coupled estrogen receptor (GPER) offers promising perspectives for the treatment of breast tumors. A peptide corresponding to part of the hinge region/AF2 domain of the human estrogen receptor α (ERα17p, residues 295–311) exerts anti-proliferative effects in various b...

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Publicat a:Cells
Autors principals: Lappano, Rosamaria, Mallet, Christophe, Rizzuti, Bruno, Grande, Fedora, Galli, Giulia Raffaella, Byrne, Cillian, Broutin, Isabelle, Boudieu, Ludivine, Eschalier, Alain, Jacquot, Yves, Maggiolini, Marcello
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627388/
https://ncbi.nlm.nih.gov/pubmed/31207943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060590
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