Φορτώνει......
Quantifying drug combination synergy along potency and efficacy axes.
Two goals motivate treating diseases with drug combinations: reduce off-target toxicity by minimizing doses (synergistic potency), and improve outcomes by escalating effect (synergistic efficacy). Established drug synergy frameworks obscure such distinction, failing to harness the potential of moder...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Syst |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6675406/ https://ncbi.nlm.nih.gov/pubmed/30797775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.01.003 |
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