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Quantifying heterogeneity and dynamics of clonal fitness in response to perturbation

The heterogeneous dynamics of clonal lineages within a cell population, in aggregate, shape both normal and pathological biological processes. Studies of clonality typically relate the fitness of clones to their relative abundance, thus requiring long-term experiments and limiting conclusions about...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Frick, Peter, Paudel, Bishal, Tyson, Darren, Quaranta, Vito
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580929/
https://ncbi.nlm.nih.gov/pubmed/25600161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24888
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