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An unbiased metric of antiproliferative drug effect in vitro
In vitro cell proliferation assays are widely used in pharmacology, molecular biology, and drug discovery. Using theoretical modeling and experimentation, we show that current antiproliferative drug effect metrics suffer from time-dependent bias, leading to inaccurate assessments of parameters such...
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| Publicado no: | Nat Methods |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887341/ https://ncbi.nlm.nih.gov/pubmed/27135974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3852 |
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