A Nonquiescent “Idling” Population State in Drug-Treated, BRAF-Mutated Melanoma

Targeted therapy is an effective standard of care in BRAF-mutated malignant melanoma. However, the duration of tumor remission varies unpredictably among patients, and relapse is almost inevitable. Here, we examine the responses of several BRAF-mutated melanoma cell lines (including isogenic subclon...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Paudel, B. Bishal, Harris, Leonard A., Hardeman, Keisha N., Abugable, Arwa A., Hayford, Corey E., Tyson, Darren R., Quaranta, Vito
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2018
Soggetti:
Systems Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883941/
https://ncbi.nlm.nih.gov/pubmed/29590606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.016
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