Intracranial Adeno-Associated Virus-Mediated Delivery of Anti-Pan Amyloid β, Amyloid β40, and Amyloid β42 Single-Chain Variable Fragments Attenuates Plaque Pathology in Amyloid Precursor Protein Mice

Accumulation of amyloid β protein (Aβ) aggregates is hypothesized to trigger a pathological cascade that causes Alzheimer's disease (AD). Active or passive immunizations targeting Aβ are therefore of great interest as potential therapeutic strategies. We have evaluated the use of recombinant an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Levites, Yona, Jansen, Karen, Smithson, Lisa A., Dakin, Rachel, Holloway, Vallie M., Das, Pritam, Golde, Todd E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674861/
https://ncbi.nlm.nih.gov/pubmed/17108166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2795-06.2006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados