Anti-Aβ(42)- and anti-Aβ(40)-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model

Accumulation and aggregation of amyloid β peptide 1–42 (Aβ(42)) in the brain has been hypothesized as triggering a pathological cascade that causes Alzheimer disease (AD). To determine whether selective targeting of Aβ(42) versus Aβ(40) or total Aβ is an effective way to prevent or treat AD, we comp...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Levites, Yona, Das, Pritam, Price, Robert W., Rochette, Marjorie J., Kostura, Lisa A., McGowan, Eileen M., Murphy, Michael P., Golde, Todd E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307561/
https://ncbi.nlm.nih.gov/pubmed/16341263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25410
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados