Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo

The Aβ peptide aggregates into amyloid plaques at presymptomatic stages of Alzheimer's disease, but the temporal relationship between plaque formation and neuronal dysfunction is poorly understood. Here, we demonstrate that the connectivity of the peripheral olfactory neural circuit is perturbe...

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Detalhes bibliográficos
Main Authors: Cao, Luxiang, Schrank, Benjamin R., Rodriguez, Steve, Benz, Eric G., Moulia, Thomas W., Rickenbacher, Gregory T., Gomez, Alexis C., Levites, Yona, Edwards, Sarah R., Golde, Todd E., Hyman, Bradley T., Barnea, Gilad, Albers, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529477/
https://ncbi.nlm.nih.gov/pubmed/22910355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2013
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