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Formation and maintenance of Alzheimer’s disease β-amyloid plaques in the absence of microglia
In Alzheimer’s disease, microglia cluster around β-amyloid deposits, suggesting that these cells are important for amyloid plaque formation, maintenance and/or clearance. We crossed two distinct APP transgenic mouse strains with CD11b-HSVTK mice, in which nearly complete ablation of microglia was ac...
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| 出版年: | Nat Neurosci |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4721582/ https://ncbi.nlm.nih.gov/pubmed/19838177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2432 |
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