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Microglia in prion diseases

Prion diseases are a group of progressive and fatal neurodegenerative disorders characterized by deposition of scrapie prion protein (PrP(Sc)) in the CNS. This deposition is accompanied by neuronal loss, spongiform change, astrogliosis, and conspicuous microglial activation. Here, we argue that micr...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Aguzzi, Adriano, Zhu, Caihong
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669569/
https://ncbi.nlm.nih.gov/pubmed/28714865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90605
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