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Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses

Molecular probes for selective identification of protein aggregates are important to advance our understanding of the molecular pathogenesis underlying cerebral amyloidoses. Here we report the chemical design of pentameric thiophene derivatives, denoted luminescent conjugated oligothiophenes (LCOs),...

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書誌詳細
主要な著者: Åslund, Andreas, Sigurdson, Christina J., Klingstedt, Therése, Grathwohl, Stefan, Bolmont, Tristan, Dickstein, Dara L., Glimsdal, Eirik, Prokop, Stefan, Lindgren, Mikael, Konradsson, Peter, Holtzman, David M., Hof, Patrick R., Heppner, Frank L., Gandy, Samuel, Jucker, Mathias, Aguzzi, Adriano, Hammarström, Per, Nilsson, K. Peter R.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886514/
https://ncbi.nlm.nih.gov/pubmed/19624097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900112v
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