Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses

Molecular probes for selective identification of protein aggregates are important to advance our understanding of the molecular pathogenesis underlying cerebral amyloidoses. Here we report the chemical design of pentameric thiophene derivatives, denoted luminescent conjugated oligothiophenes (LCOs),...

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Autors principals: Åslund, Andreas, Sigurdson, Christina J., Klingstedt, Therése, Grathwohl, Stefan, Bolmont, Tristan, Dickstein, Dara L., Glimsdal, Eirik, Prokop, Stefan, Lindgren, Mikael, Konradsson, Peter, Holtzman, David M., Hof, Patrick R., Heppner, Frank L., Gandy, Samuel, Jucker, Mathias, Aguzzi, Adriano, Hammarström, Per, Nilsson, K. Peter R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886514/
https://ncbi.nlm.nih.gov/pubmed/19624097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900112v
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