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Microglia as Dynamic and Essential Components of the Amyloid Hypothesis
In this issue, Griciuc et al investigate the Alzheimer’s disease risk gene, CD33. AD brains have increased CD33 and CD33-positive microglia. Mice lacking CD33 have less AD pathology suggesting a role of microglia for Aβ clearance and development of future therapies.
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| Publié dans: | Neuron |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6494439/ https://ncbi.nlm.nih.gov/pubmed/23719156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.05.007 |
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