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Microglia as Dynamic and Essential Components of the Amyloid Hypothesis

In this issue, Griciuc et al investigate the Alzheimer’s disease risk gene, CD33. AD brains have increased CD33 and CD33-positive microglia. Mice lacking CD33 have less AD pathology suggesting a role of microglia for Aβ clearance and development of future therapies.

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Bibliografski detalji
Izdano u:Neuron
Glavni autori: Gandy, Sam, Heppner, Frank L.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494439/
https://ncbi.nlm.nih.gov/pubmed/23719156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.05.007
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