Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

Microglial cells closely interact with senile plaques in Alzheimer’s disease and acquire the morphological appearance of an activated phenotype. The significance of this microglial phenotype and the impact of microglia for disease progression have remained controversial. To uncover and characterize...

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Detalhes bibliográficos
Main Authors: Krabbe, Grietje, Halle, Annett, Matyash, Vitali, Rinnenthal, Jan L., Eom, Gina D., Bernhardt, Ulrike, Miller, Kelly R., Prokop, Stefan, Kettenmann, Helmut, Heppner, Frank L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620049/
https://ncbi.nlm.nih.gov/pubmed/23577177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060921
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