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The adenosine generating enzymes CD39/CD73 control microglial processes ramification in the mouse brain

Microglial cells invade the brain as amoeboid precursors and acquire a highly ramified morphology in the postnatal brain. Microglia express all essential purinergic elements such as receptors, nucleoside transporters and ecto-enzymes, including CD39 (NTPDase1) and CD73 (5'-nucleotidase), which...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Matyash, Marina, Zabiegalov, Oleksandr, Wendt, Stefan, Matyash, Vitali, Kettenmann, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380357/
https://ncbi.nlm.nih.gov/pubmed/28376099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175012
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