Changes in CD73, CD39 and CD26 expression on T-lymphocytes of ANCA-associated vasculitis patients suggest impairment in adenosine generation and turn-over

Extracellular adenosine, generated via the concerted action of CD39 and CD73, contributes to T-cell differentiation and function. Adenosine concentrations are furthermore influenced by adenosine deaminase binding protein CD26. Because aberrant T-cell phenotypes had been reported in anti-neutrophil c...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Kling, Lovis, Benck, Urs, Breedijk, Annette, Leikeim, Lisa, Heitzmann, Marianne, Porubsky, Stefan, Krämer, Bernhard K., Yard, Benito A., Kälsch, Anna-Isabelle
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601951/
https://ncbi.nlm.nih.gov/pubmed/28916770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12011-4
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