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The precision of axon targeting of mouse olfactory sensory neurons requires the BACE1 protease
The β-site amyloid precursor protein cleaving enzyme 1 (BACE1) is necessary to generate the Aβ peptide, which is implicated in Alzheimer's disease pathology. Studies show that the expression of BACE1 and its protease activity are tightly regulated, but the physiological function of BACE1 remain...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262176/ https://ncbi.nlm.nih.gov/pubmed/22355745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00231 |
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