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The precision of axon targeting of mouse olfactory sensory neurons requires the BACE1 protease

The β-site amyloid precursor protein cleaving enzyme 1 (BACE1) is necessary to generate the Aβ peptide, which is implicated in Alzheimer's disease pathology. Studies show that the expression of BACE1 and its protease activity are tightly regulated, but the physiological function of BACE1 remain...

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Detalhes bibliográficos
Main Authors: Cao, Luxiang, Rickenbacher, Gregory T., Rodriguez, Steve, Moulia, Thomas W., Albers, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262176/
https://ncbi.nlm.nih.gov/pubmed/22355745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00231
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