Á lódáil...
Holdase activity of secreted Hsp70 masks amyloid-β42 neurotoxicity in Drosophila
Alzheimer’s disease (AD) is the most prevalent of a large group of related proteinopathies for which there is currently no cure. Here, we used Drosophila to explore a strategy to block Aβ42 neurotoxicity through engineering of the Heat shock protein 70 (Hsp70), a chaperone that has demonstrated neur...
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| Foilsithe in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5024614/ https://ncbi.nlm.nih.gov/pubmed/27531960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608045113 |
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