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Engineered Hsp70 chaperones prevent Aβ42-induced memory impairments in a Drosophila model of Alzheimer’s disease

Proteinopathies constitute a group of diseases in which certain proteins are abnormally folded leading to aggregation and eventual cell failure. Most neurodegenerative diseases belong to protein misfolding disorders and, among them, Alzheimer’s disease (AD) is the most prevalent. AD is characterized...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Martín-Peña, Alfonso, Rincón-Limas, Diego E., Fernandez-Fúnez, Pedro
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028656/
https://ncbi.nlm.nih.gov/pubmed/29967544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28341-w
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