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Engineered Hsp70 chaperones prevent Aβ42-induced memory impairments in a Drosophila model of Alzheimer’s disease

Proteinopathies constitute a group of diseases in which certain proteins are abnormally folded leading to aggregation and eventual cell failure. Most neurodegenerative diseases belong to protein misfolding disorders and, among them, Alzheimer’s disease (AD) is the most prevalent. AD is characterized...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Martín-Peña, Alfonso, Rincón-Limas, Diego E., Fernandez-Fúnez, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028656/
https://ncbi.nlm.nih.gov/pubmed/29967544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28341-w
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