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Engineered Hsp70 chaperones prevent Aβ42-induced memory impairments in a Drosophila model of Alzheimer’s disease

Proteinopathies constitute a group of diseases in which certain proteins are abnormally folded leading to aggregation and eventual cell failure. Most neurodegenerative diseases belong to protein misfolding disorders and, among them, Alzheimer’s disease (AD) is the most prevalent. AD is characterized...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Martín-Peña, Alfonso, Rincón-Limas, Diego E., Fernandez-Fúnez, Pedro
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028656/
https://ncbi.nlm.nih.gov/pubmed/29967544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28341-w
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