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Interaction of Survival and Death Signaling in Basal Forebrain Neurons: Roles of Neurotrophins and Proneurotrophins

Proneurotrophins bind with high affinity to p75 neurotrophin receptor (p75(NTR)) and lack the capacity to bind Trk receptors, suggesting that proneurotrophins can elicit apoptosis via p75(NTR) even in cells expressing survival-promoting Trk receptors. In the CNS, basal forebrain (BF) neurons are par...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Volosin, Marta, Song, Wenyu, Almeida, Ramiro D., Kaplan, David R., Hempstead, Barbara L., Friedman, Wilma J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674285/
https://ncbi.nlm.nih.gov/pubmed/16855103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1560-06.2006
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