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The p75 Neurotrophin Receptor Facilitates TrkB Signaling and Function in Rat Hippocampal Neurons

Neurotrophins activate Trk receptor signaling to support neuronal survival and many aspects of neuronal function. Early studies demonstrated that TrkA formed a complex with the p75 neurotrophin receptor (p75(NTR)), which increased the affinity and selectivity of NGF binding, however, whether interac...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Zanin, Juan P., Montroull, Laura E., Volosin, Marta, Friedman, Wilma J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828739/
https://ncbi.nlm.nih.gov/pubmed/31736712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00485
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