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Cholesterol Loss Enhances TrkB Signaling in Hippocampal Neurons Aging in Vitro
Binding of the neurotrophin brain-derived neurotrophic factor (BDNF) to the TrkB receptor is a major survival mechanism during embryonic development. In the aged brain, however, BDNF levels are low, suggesting that if TrkB is to play a role in survival at this stage additional mechanisms must have d...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Cell Biology
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366859/ https://ncbi.nlm.nih.gov/pubmed/18287532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-09-0897 |
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