Antidepressant Drugs Transactivate TrkB Neurotrophin Receptors in the Adult Rodent Brain Independently of BDNF and Monoamine Transporter Blockade

BACKGROUND: Antidepressant drugs (ADs) have been shown to activate BDNF (brain-derived neurotrophic factor) receptor TrkB in the rodent brain but the mechanism underlying this phenomenon remains unclear. ADs act as monoamine reuptake inhibitors and after prolonged treatments regulate brain bdnf mRNA...

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Main Authors: Rantamäki, Tomi, Vesa, Liisa, Antila, Hanna, Di Lieto, Antonio, Tammela, Päivi, Schmitt, Angelika, Lesch, Klaus-Peter, Rios, Maribel, Castrén, Eero
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110188/
https://ncbi.nlm.nih.gov/pubmed/21666748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020567
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