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Differential effects of BDNF and neurotrophin 4 (NT4) on endocytic sorting of TrkB receptors

Neurotrophins are a family of growth factors playing key roles in the survival, development, and function of neurons. The neurotrophins BDNF and NT4 both bind to and activate TrkB receptors, however, they mediate distinct neuronal functions. The molecular mechanism of how TrkB activation by BDNF and...

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Detalles Bibliográficos
Publicado en:J Neurochem
Main Authors: Proenca, Catia C., Song, Minseok, Lee, Francis S.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961580/
https://ncbi.nlm.nih.gov/pubmed/27216821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13676
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