Slitrk5 mediates BDNF-dependent TrkB receptor trafficking and signaling

Recent studies in humans and in genetic mouse models have identified Slitrks as candidate genes for neuropsychiatric disorders. All Slitrk isotypes are highly expressed in the CNS, where they mediate neurite outgrowth, synaptogenesis and neuronal survival. However, the molecular mechanisms underlyin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dev Cell
Prif Awduron: Song, Minseok, Giza, Joanna, Proenca, Catia C., Jing, Deqiang, Elliott, Mark, Dincheva, Iva, Shmelkov, Sergey V., Kim, Jihye, Schreiner, Ryan, Huang, Shu-Hong, Castrén, Eero, Prekeris, Rytis, Hempstead, Barbara L., Chao, Moses V., Dictenberg, Jason B., Rafii, Shahin, Chen, Zhe-Yu, Rodriguez-Boulan, Enrique, Lee, Francis S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784688/
https://ncbi.nlm.nih.gov/pubmed/26004511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.04.009
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