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TrkB deubiquitylation by USP8 regulates receptor levels and BDNF-dependent neuronal differentiation
Ubiquitylation of receptor tyrosine kinases (RTKs) regulates both the levels and functions of these receptors. The neurotrophin receptor TrkB (also known as NTRK2), a RTK, is ubiquitylated upon activation by brain-derived neurotrophic factor (BDNF) binding. Although TrkB ubiquitylation has been demo...
Gardado en:
| Publicado en: | J Cell Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists Ltd
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7774901/ https://ncbi.nlm.nih.gov/pubmed/33288548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.247841 |
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