ProNGF Induces PTEN via p75(NTR) to Suppress Trk-Mediated Survival Signaling in Brain Neurons

Proneurotrophins and mature neurotrophins activate different signaling pathways with distinct effects on their target cells: proneurotrophins can induce apoptotic signaling via p75(NTR), whereas mature neurotrophins activate Trk receptors to influence survival and differentiation. Here, we demonstra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Song, Wenyu, Volosin, Marta, Cragnolini, Andrea B., Hempstead, Barbara L., Friedman, Wilma J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2010
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996105/
https://ncbi.nlm.nih.gov/pubmed/21084616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2581-10.2010
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