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ProNGF Induces PTEN via p75(NTR) to Suppress Trk-Mediated Survival Signaling in Brain Neurons
Proneurotrophins and mature neurotrophins activate different signaling pathways with distinct effects on their target cells: proneurotrophins can induce apoptotic signaling via p75(NTR), whereas mature neurotrophins activate Trk receptors to influence survival and differentiation. Here, we demonstra...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996105/ https://ncbi.nlm.nih.gov/pubmed/21084616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2581-10.2010 |
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