Induction of Proneurotrophins and Activation of p75(NTR)-Mediated Apoptosis via Neurotrophin Receptor-Interacting Factor in Hippocampal Neurons after Seizures

Seizure-induced damage elicits a loss of hippocampal neurons mediated to a great extent by the p75 neurotrophin receptor (NTR). Proneurotrophins, which are potent apoptosis-inducing ligands for p75(NTR), were increased in the hippocampus, particularly in astrocytes, by pilocarpine-induced seizures;...

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Détails bibliographiques
Auteurs principaux: Volosin, Marta, Trotter, Christy, Cragnolini, Andrea, Kenchappa, Rajappa S., Light, Matthew, Hempstead, Barbara L., Carter, Bruce D., Friedman, Wilma J.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2008
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578816/
https://ncbi.nlm.nih.gov/pubmed/18815271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2841-08.2008
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