Interaction of Survival and Death Signaling in Basal Forebrain Neurons: Roles of Neurotrophins and Proneurotrophins

Proneurotrophins bind with high affinity to p75 neurotrophin receptor (p75(NTR)) and lack the capacity to bind Trk receptors, suggesting that proneurotrophins can elicit apoptosis via p75(NTR) even in cells expressing survival-promoting Trk receptors. In the CNS, basal forebrain (BF) neurons are par...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Volosin, Marta, Song, Wenyu, Almeida, Ramiro D., Kaplan, David R., Hempstead, Barbara L., Friedman, Wilma J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674285/
https://ncbi.nlm.nih.gov/pubmed/16855103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1560-06.2006
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