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Interaction of Survival and Death Signaling in Basal Forebrain Neurons: Roles of Neurotrophins and Proneurotrophins

Proneurotrophins bind with high affinity to p75 neurotrophin receptor (p75(NTR)) and lack the capacity to bind Trk receptors, suggesting that proneurotrophins can elicit apoptosis via p75(NTR) even in cells expressing survival-promoting Trk receptors. In the CNS, basal forebrain (BF) neurons are par...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Volosin, Marta, Song, Wenyu, Almeida, Ramiro D., Kaplan, David R., Hempstead, Barbara L., Friedman, Wilma J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674285/
https://ncbi.nlm.nih.gov/pubmed/16855103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1560-06.2006
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