טוען...
Moderate Reduction of γ-Secretase Attenuates Amyloid Burden and Limits Mechanism-Based Liabilities
Although γ-secretase is recognized as a therapeutic target for Alzheimer's disease, side effects associated with strong inhibition of this aspartyl protease raised serious concerns regarding this therapeutic strategy. However, it is not known whether moderate inhibition of this enzyme will allo...
שמור ב:
| הוצא לאור ב: | J Neurosci |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Society for Neuroscience
2007
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672827/ https://ncbi.nlm.nih.gov/pubmed/17913918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2152-07.2007 |
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