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Transcription-mediated replication hindrance: a major driver of genome instability
Genome replication involves dealing with obstacles that can result from DNA damage but also from chromatin alterations, topological stress, tightly bound proteins or non-B DNA structures such as R loops. Experimental evidence reveals that an engaged transcription machinery at the DNA can either enha...
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| Publicado no: | Genes Dev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672053/ https://ncbi.nlm.nih.gov/pubmed/31123061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.324517.119 |
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