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Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability
Sen1 of S. cerevisiae is a known component of the NRD complex implicated in transcription termination of nonpolyadenylated as well as some polyadenylated RNA polymerase II transcripts. We now show that Sen1 helicase possesses a wider function by restricting the occurrence of RNA:DNA hybrids that may...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314950/ https://ncbi.nlm.nih.gov/pubmed/21211720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.007 |
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