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Pcf11 orchestrates transcription termination pathways in yeast

In Saccharomyces cerevisiae, short noncoding RNA (ncRNA) generated by RNA polymerase II (Pol II) are terminated by the NRD complex consisting of Nrd1, Nab3, and Sen1. We now show that Pcf11, a component of the cleavage and polyadenylation complex (CPAC), is also generally required for NRD-dependent...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Grzechnik, Pawel, Gdula, Michal Ryszard, Proudfoot, Nick J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403260/
https://ncbi.nlm.nih.gov/pubmed/25877920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.251470.114
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