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WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription

Nuclear gene transcription is coordinated with transcript release from the chromatin template and messenger RNA (mRNA) export to the cytoplasm. Here we describe the role of nuclear-localized kinase WNK1 (with no lysine [K] 1) in the mammalian mRNA export pathway even though it was previously establi...

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Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Volanakis, Adam, Kamieniarz-Gdula, Kinga, Schlackow, Margarita, Proudfoot, Nick J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749165/
https://ncbi.nlm.nih.gov/pubmed/29196535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.303677.117
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