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AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination

RNA Polymerase II (Pol II) termination is dependent on RNA processing signals as well as specific terminator elements located downstream of the poly(A) site. One of the two major terminator classes described so far is the Co-Transcriptional Cleavage (CoTC) element. We show that homopolymer A/T tract...

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Bibliografiske detaljer
Main Authors: White, Eleanor, Kamieniarz-Gdula, Kinga, Dye, Michael J., Proudfoot, Nick J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561976/
https://ncbi.nlm.nih.gov/pubmed/23258704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1335
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