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AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination

RNA Polymerase II (Pol II) termination is dependent on RNA processing signals as well as specific terminator elements located downstream of the poly(A) site. One of the two major terminator classes described so far is the Co-Transcriptional Cleavage (CoTC) element. We show that homopolymer A/T tract...

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Bibliografische gegevens
Hoofdauteurs: White, Eleanor, Kamieniarz-Gdula, Kinga, Dye, Michael J., Proudfoot, Nick J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561976/
https://ncbi.nlm.nih.gov/pubmed/23258704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1335
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