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HUMAN NUCLEAR DICER RESTRICTS THE DELETERIOUS ACCUMULATION OF ENDOGENOUS DOUBLE STRAND RNA
Dicer is a central enzymatic player in RNA interference (RNAi) pathways that acts to regulate gene expression in nearly all eukaryotes. Although the cytoplasmic function of Dicer is well-documented in mammals, its nuclear function remains obscure. Here we show that Dicer is present in both the nucle...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4129937/ https://ncbi.nlm.nih.gov/pubmed/24814348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2827 |
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