Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage

The endoribonuclease Dicer is a key component of the human RNA interference pathway and is known for its role in cytoplasmic microRNA production. Recent findings suggest that noncanonical Dicer generates small noncoding RNA to mediate the DNA damage response (DDR). Here, we show that human Dicer is...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Cell Biol
Hlavní autoři: Burger, Kaspar, Schlackow, Margarita, Potts, Martin, Hester, Svenja, Mohammed, Shabaz, Gullerova, Monika
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551710/
https://ncbi.nlm.nih.gov/pubmed/28642363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201612131
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky